Field Name | Description |
---|---|
% Effect | The magnitude of the effect (e.g., % mortality; change in weight; change in length; percent hatch; etc.). |
Analyte | The chemical substance used to create the exposure. |
CAS | CAS registry number is a unique numerical identifier assigned by Chemical Abstract Service (CAS) to a chemical substance. |
COLL | Where the animal was obtained: C (cultured-reared in laboratory); W (collected from wild); N/I (No Information); N/R (Not Reported). |
Comments | Commonly supports the effects data. |
Common name | Common name of the test animal. |
Control | The control response for the observed effect (e.g., survival, growth, reproduction; etc.). |
Dose | The frequency with which the contaminant was applied during the test. |
Duration | The duration of the exposure period: hr (hours); d (days) wk (weeks), mo (months), yr (years). |
Effect | The type of toxicological effect observed in the test animal (e.g., survival, growth, reproduction). |
ERED ID | Unique identification number autogenerated by database. |
ExpConc | The exposure concentration and units. |
Fraction | The test animal tissue used to determine tissue residue (e.g., whole body, soft tissue, liver, etc.). |
Genus Species | Scientific name of the test animal. |
Media | Type of water used to test animal: FW (freshwater); SW (saltwater) |
Mix | Whether the analyte was tested as part of a mixture of analytes or individually: yes (part of mixture), no (single), or N/I (No information). |
Risk | Summary of the risk (e.g., ED, NOED, LOED) an analyte might pose to the test animal. Previously, many risk numbers were assigned to results. Going forward ERED will not report a risk number unless it is reported in the study. |
Route | The route by which the analyte was intended to enter the body: aquatic; diet; injection. |
Signif | Whether the effect was significantly different, usually compared to the control for laboratory studies: Yes (significant); No (not significant). |
Source | Reference from which data was obtained. |
Spiked | Whether the analyte was spiked into the route (aquatic, diet, sediment, injection): yes (analyte spiked), no (analyte not spiked) |
ST | Study type: L (Lab); F (Field); L/F (Lab/Field); Meso (Mesocosm); Micro (Microcosm); N/I (No Information). |
Stage | Life stage of the test animal (e.g., egg, larval, juvenile, adult). |
Tissue ww (mg/kg) | Tissue residue of analyte in the test animal tissue (mg/kg wet weight). |
Trend | The trend of the effect, usually compared to the control for laboratory studies: INC (increase); DEC (decrease), NEF (No effect). |
You are viewing Chordata: Vert (fishes; non-salmonid) and Dioxins
Genus Species | ERED ID | ST | Common | Stage | COLL | Analyte | CAS | MX | SPK | H2O | Route | CONC | Dose | DUR | Residue mg/kg ww |
Fraction | Effect | Trend | Signif | % Effect | Control | Risk | Comments | Source |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyprinus carpio | 19599 | L | Common carp | N/R | C | 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin | 57653-85-7 | N | Y | FW | injection | 0.00031 mg/kg bw | 1x | 14 d | 0.002 | liver | enzyme(s) | INC | Y | N/I | N/I | LOEC | induction of EROD activity | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19600 | L | Common carp | N/R | C | 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin | 57653-85-7 | N | Y | FW | injection | 0.0015 mg/kg bw | 1x | 14 d | 0.0122 | liver | enzyme(s) | INC | Y | N/I | N/I | LOEC | induction P450 1A protein | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19614 | L | Common carp | N/R | C | 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin | 57653-85-7 | N | Y | FW | injection | 0.5 nmol/kg bw | 1x | 14 d | 1.21 | liver | enzyme(s) | INC | Y | N/I | N/I | ED 50 | induction of EROD activity | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19615 | L | Common carp | N/R | C | 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin | 57653-85-7 | N | Y | FW | injection | 0.536 nmol/kg bw | 1x | 14 d | 0.678 | liver | enzyme(s) | INC | Y | N/I | N/I | ED 50 | induction P450 1A protein | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19612 | L | Common carp | N/R | C | 1,2,3,7,8-Pentachlorodibenzo-p-dioxin | 40321-76-4 | N | Y | FW | injection | 0.025 nmol/kg bw | 1x | 14 d | 0.129 | liver | enzyme(s) | INC | Y | N/I | N/I | ED 50 | induction of EROD activity | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19613 | L | Common carp | N/R | C | 1,2,3,7,8-Pentachlorodibenzo-p-dioxin | 40321-76-4 | N | Y | FW | injection | 0.025 nmol/kg bw | 1x | 14 d | 0.156 | liver | enzyme(s) | INC | Y | N/I | N/I | ED 50 | induction P450 1A protein | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19597 | L | Common carp | N/R | C | 1,2,3,7,8-Pentachlorodibenzo-p-dioxin | 40321-76-4 | N | Y | FW | injection | 0.000002 mg/kg bw | 1x | 14 d | 6E-005 | liver | enzyme(s) | INC | Y | N/I | N/I | LOEC | induction of EROD activity | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19598 | L | Common carp | N/R | C | 1,2,3,7,8-Pentachlorodibenzo-p-dioxin | 40321-76-4 | N | Y | FW | injection | 0.00001 mg/kg bw | 1x | 14 d | 0.00064 | liver | enzyme(s) | INC | Y | N/I | N/I | LOEC | induction P450 1A protein | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Danio rerio | 16879 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.177 mg/kg | 2%bw/day | 42 d | 0.012108 | whole body | growth | DEC | Y | N/R | N/I | N/R | body weight decreased | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 16880 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.177 mg/kg | 2%bw/day | 42 d | 0.012108 | whole body | reproduction | DEC | Y | 100% | N/I | N/R | spawning stopped after week 1 | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 16881 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.0195 mg/kg | 2%bw/day | 63 d | 0.003342 | whole body | reproduction | DEC | Y | 100% | N/I | N/R | spawning stopped after week 5 | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 16883 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.0195 mg/kg | 2%bw/day | 63 d | 0.003342 | whole body | growth | DEC | Y | N/R | N/I | N/R | body weight decreased | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 16886 | L | zebra danio | egg | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.00132 mg/kg | 2%bw/day | 63 d | 0.000468 | whole body | development | INC | Y | 46% | N/I | N/R | 46% unfertilized/abnormal 5 hpf | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 16890 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.177 mg/kg | 2%bw/day | 42 d | 0.012108 | whole body | mortality | INC | Y | 23% | N/I | N/R | mortality 23% | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 16892 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.00132 mg/kg | 2%bw/day | 63 d | 0.000468 | whole body | growth | NEF | N | N/R | N/I | N/R | no difference in body weight | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 16893 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.0195 mg/kg | 2%bw/day | 63 d | 0.003342 | whole body | mortality | NEF | N | N/R | N/I | N/R | moraltiy <2% | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 16894 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.00132 mg/kg | 2%bw/day | 63 d | 0.000468 | whole body | mortality | NEF | N | N/R | N/I | N/R | moraltiy <2% | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 16895 | L | zebra danio | larvae | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.00132 mg/kg | 2%bw/day | 63 d | 0.000468 | whole body | development | INC | N | 41% | N/I | N/R | 41% abnormal 144 hpf no difference | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 17433 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.00132 mg/kg | 2%bw/day | 63 d | 0.000468 | whole body | accumulation | INC | N/I | N/R | N/R |
dose dependent accumulation |
Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
|
Danio rerio | 17434 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.0195 mg/kg | 2%bw/day | 63 d | 0.003342 | whole body | accumulation | INC | N/I | N/R | N/R |
dose dependent accumulation |
Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
|
Danio rerio | 17435 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.177 mg/kg | 2%bw/day | 42 d | 0.012108 | whole body | accumulation | INC | N/I | N/R | N/R |
dose dependent accumulation |
Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
|
Danio rerio | 17436 | L | zebra danio | egg | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.00132 mg/kg | 2%bw/day | 63 d | 0.000468 | whole body | accumulation | INC | N/I | N/R | N/R |
accumulated in egg |
Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
|
Danio rerio | 17437 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.00132 mg/kg | 2%bw/day | 63 d | 0.000468 | whole body | histopathology | DEC | Y | 38% | N/I | N/R | 38% vitellogenic oocytes | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 17438 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.0195 mg/kg | 2%bw/day | 63 d | 0.003342 | whole body | histopathology | DEC | Y | 5% | N/I | N/R | 5% vitellogenic oocytes | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 17439 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.00132 mg/kg | 2%bw/day | 63 d | 0.000468 | whole body | histopathology | INC | Y | 13% | N/I | N/R | 13% atretic follicles | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 17440 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.0195 mg/kg | 2%bw/day | 63 d | 0.003342 | whole body | histopathology | INC | Y | 18% | N/I | N/R | 5% atretic follicles | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 17441 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.00132 mg/kg | 2%bw/day | 63 d | 0.000468 | whole body | biochemistry | INC | Y | N/R | N/I | N/R | induced EROD activity | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 17442 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.0195 mg/kg | 2%bw/day | 63 d | 0.003342 | whole body | biochemistry | INC | Y | N/R | N/I | N/R | induced EROD activity | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 17443 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.00132 mg/kg | 2%bw/day | 63 d | 0.000468 | whole body | biochemistry | INC | Y | N/R | N/I | N/R | induced GR activity | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 17444 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.0195 mg/kg | 2%bw/day | 63 d | 0.003342 | whole body | biochemistry | INC | Y | N/R | N/I | N/R | induced GR activity | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 17445 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.0195 mg/kg | 2%bw/day | 63 d | 0.003342 | whole body | gene expression | INC | N/I | N/R | N/I | N/R | changes in gene expression increased | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Danio rerio | 17446 | L | zebra danio | adult | C | 2,3,7,8-Tetrabromodibenzo-p-dioxin | 50585-41-6 | N | Y | FW | diet | 0.00132 mg/kg | 2%bw/day | 63 d | 0.000468 | whole body | gene expression | INC | N/I | N/R | N/I | N/R | changes in gene expression increased | Halden et al. 2011. Retention and maternal transfer of bromi.... Aquat Toxicol 102:150-161. |
Cyprinus carpio | 19608 | L | Common carp | N/R | C | 2,3,7,8-Tetrachlorodibenzofuran | 51207-31-9 | N | Y | FW | injection | 17.75 nmol/kg bw | 1x | 14 d | 1.413 | liver | enzyme(s) | INC | Y | N/I | N/I | ED 50 | induction of EROD activity | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19609 | L | Common carp | N/R | C | 2,3,7,8-Tetrachlorodibenzofuran | 51207-31-9 | N | Y | FW | injection | 18.63 nmol/kg bw | 1x | 14 d | 0.396 | liver | enzyme(s) | INC | Y | N/I | N/I | ED 50 | induction P450 1A protein | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19594 | L | Common carp | N/R | C | 2,3,7,8-Tetrachlorodibenzofuran | 51207-31-9 | N | Y | FW | injection | 0.01051 mg/kg bw | 1x | 14 d | 0.0056 | liver | enzyme(s) | INC | Y | N/I | N/I | LOEC | induction P450 1A protein | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Danio rerio | 16334 | L | zebra danio | adult | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | N/I | N/I | N/I | 0.02 | whole body | biochemistry | N/I | N/I | N/I | N/I | IP 1200 | CYP1A - artery | Bugiak and Weber. 2009. Hepatic and vascular mRNA expression in .... Aquat Toxicol 95:299-306. |
Danio rerio | 16335 | L | zebra danio | adult | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | N/I | N/I | N/I | 0.02 | whole body | biochemistry | N/I | N/I | N/I | N/I | IP 500 | CYP1B1 - artery | Bugiak and Weber. 2009. Hepatic and vascular mRNA expression in .... Aquat Toxicol 95:299-306. |
Danio rerio | 16336 | L | zebra danio | adult | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | N/I | N/I | N/I | 0.02 | whole body | biochemistry | N/I | N/I | N/I | N/I | IP 2800 | CYP1C1 - artery | Bugiak and Weber. 2009. Hepatic and vascular mRNA expression in .... Aquat Toxicol 95:299-306. |
Danio rerio | 16337 | L | zebra danio | adult | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | N/I | N/I | N/I | 0.02 | whole body | biochemistry | N/I | N/I | N/I | N/I | IP 650 | CYP1C2 - artery | Bugiak and Weber. 2009. Hepatic and vascular mRNA expression in .... Aquat Toxicol 95:299-306. |
Danio rerio | 16338 | L | zebra danio | adult | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | N/I | N/I | N/I | 0.02 | whole body | biochemistry | N/I | N/I | N/I | N/I | IP 230 | COX-2a - artery | Bugiak and Weber. 2009. Hepatic and vascular mRNA expression in .... Aquat Toxicol 95:299-306. |
Danio rerio | 16339 | L | zebra danio | adult | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | N/I | N/I | N/I | 0.02 | whole body | biochemistry | N/I | N/I | N/I | N/I | IP 430 | COX-2b - artery | Bugiak and Weber. 2009. Hepatic and vascular mRNA expression in .... Aquat Toxicol 95:299-306. |
Danio rerio | 16340 | L | zebra danio | adult | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | N/I | N/I | N/I | 0.02 | whole body | biochemistry | N/I | N/I | N/I | N/I | IP 1000 | CYP1A - liver | Bugiak and Weber. 2009. Hepatic and vascular mRNA expression in .... Aquat Toxicol 95:299-306. |
Danio rerio | 16341 | L | zebra danio | adult | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | N/I | N/I | N/I | 0.02 | whole body | biochemistry | N/I | N/I | N/I | N/I | IP 200 | CYP1B1 - liver | Bugiak and Weber. 2009. Hepatic and vascular mRNA expression in .... Aquat Toxicol 95:299-306. |
Danio rerio | 16342 | L | zebra danio | adult | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | N/I | N/I | N/I | 0.02 | whole body | biochemistry | N/I | N/I | N/I | N/I | IP 1300 | CYP1C1 - liver | Bugiak and Weber. 2009. Hepatic and vascular mRNA expression in .... Aquat Toxicol 95:299-306. |
Danio rerio | 16343 | L | zebra danio | adult | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | N/I | N/I | N/I | 0.02 | whole body | biochemistry | N/I | N/I | N/I | N/I | IP 200 | CYP1C2 - liver | Bugiak and Weber. 2009. Hepatic and vascular mRNA expression in .... Aquat Toxicol 95:299-306. |
Danio rerio | 16344 | L | zebra danio | adult | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | N/I | N/I | N/I | 0.02 | whole body | biochemistry | N/I | N/I | N/I | N/I | IP 220 | COX-1 - liver | Bugiak and Weber. 2009. Hepatic and vascular mRNA expression in .... Aquat Toxicol 95:299-306. |
Danio rerio | 16345 | L | zebra danio | adult | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | N/I | N/I | N/I | 0.02 | whole body | biochemistry | N/I | N/I | N/I | N/I | IP 190 | COX-2a - liver | Bugiak and Weber. 2009. Hepatic and vascular mRNA expression in .... Aquat Toxicol 95:299-306. |
Danio rerio | 16346 | L | zebra danio | adult | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | N/I | N/I | N/I | 0.02 | whole body | biochemistry | N/I | N/I | N/I | N/I | IP 210 | COX-2b - liver | Bugiak and Weber. 2009. Hepatic and vascular mRNA expression in .... Aquat Toxicol 95:299-306. |
Cyprinus carpio | 19601 | L | Common carp | N/R | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | 0.00003 mg/kg bw | 1x | 14 d | 0.00034 | liver | enzyme(s) | INC | Y | N/I | N/I | LOEC | induction of EROD activity | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19602 | L | Common carp | N/R | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | 0.00003 mg/kg bw | 1x | 14 d | 0.00034 | liver | enzyme(s) | INC | Y | N/I | N/I | LOEC | induction P450 1A protein | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19606 | L | Common carp | N/R | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | 0.069 nmol/kg bw | 1x | 14 d | 0.099 | liver | enzyme(s) | INC | Y | N/I | N/I | ED 50 | induction of EROD activity | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19607 | L | Common carp | N/R | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | 0.084 nmol/kg bw | 1x | 14 d | 0.059 | liver | enzyme(s) | INC | Y | N/I | N/I | ED 50 | induction P450 1A protein | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19616 | L | Common carp | N/R | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | 0.166 nmol/kg bw | 1x | 14 d | 0.067 | liver | enzyme(s) | INC | Y | N/I | N/I | ED 50 | induction of EROD activity | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19617 | L | Common carp | N/R | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | 0.059 nmol/kg bw | 1x | 14 d | 0.074 | liver | enzyme(s) | INC | Y | N/I | N/I | ED 50 | induction P450 1A protein | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19592 | L | Common carp | N/R | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | 0.00003 mg/kg bw | 1x | 14 d | 0.00013 | liver | enzyme(s) | INC | Y | N/I | N/I | LOEC | induction of EROD activity | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 19593 | L | Common carp | N/R | C | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | FW | injection | 0.00003 mg/kg bw | 1x | 14 d | 0.00013 | liver | enzyme(s) | INC | Y | N/I | N/I | LOEC | induction P450 1A protein | van der Weiden et al. 1994. Relative potencies of polychlorinated di.... Aquat Toxicol 29:163-182. |
Cyprinus carpio | 4652 | L | Common carp | N/I | N/I | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | N/I | injection | N/I | N/I | 80 | 0.003 | whole body | mortality | N/I | N/I | N/I | N/I | LD 50 | 80 Day LD50 For mortality | Kleeman et al. 1988. Species differences in 2, 3, 7, 8-tetrac.... Fund Appl Toxicol 10:206-213. |
Cyprinus carpio | 4660 | L | Common carp | N/I | N/I | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | N/I | injection | 1 µg/kg | N/I | 80 | 0.001 | whole body | morphology | N/I | N/I | Yes | N/I | LOEC | hyperpigmentation | Kleeman et al. 1988. Species differences in 2, 3, 7, 8-tetrac.... Fund Appl Toxicol 10:206-213. |
Cyprinus carpio | 4666 | L | Common carp | N/I | N/I | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | N/I | injection | 25 µg/kg | N/I | 80 | 0.025 | whole body | morphology | N/I | N/I | Yes | N/I | LOEC | Fin necrosis, cutaneous hemorrhage | Kleeman et al. 1988. Species differences in 2, 3, 7, 8-tetrac.... Fund Appl Toxicol 10:206-213. |
Cyprinus carpio | 4672 | L | Common carp | N/I | N/I | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | N | Y | N/I | injection | 1 µg/kg | N/I | 80 | 0.001 | whole body | mortality | NEF | N/I | N/I | N/I | NOEC | N/I | Kleeman et al. 1988. Species differences in 2, 3, 7, 8-tetrac.... Fund Appl Toxicol 10:206-213. |
Cyprinus carpio | 15435 | F | Common carp | adult | W | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | Y | N | FW | in situ | N/I | N/I | N/I | 0.00098 | muscle | physiological | N/I | N/I | N/I | N/I | IP 180 | Males, total CYP content, 0.93-8.7 TEQ/L | Sakamoto et al. 2003. Cytochrome P450 induction and gonadal st.... Chemosphere 51:491-500. |
Cyprinus carpio | 15436 | F | Common carp | adult | W | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | Y | N | FW | in situ | N/I | N/I | N/I | 0.00037 | muscle | physiological | N/I | N/I | N/I | N/I | IP 800 | Females, total CYP content, 0.93-8.7 TEQ/L | Sakamoto et al. 2003. Cytochrome P450 induction and gonadal st.... Chemosphere 51:491-500. |
Cyprinus carpio | 15437 | F | Common carp | adult | W | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | Y | N | FW | in situ | N/I | N/I | N/I | 0.00098 | muscle | physiological | N/I | N/I | N/I | N/I | ED 57 | males, serum estrogen, 0.93-8.7 TEQ/L | Sakamoto et al. 2003. Cytochrome P450 induction and gonadal st.... Chemosphere 51:491-500. |
Cyprinus carpio | 15438 | F | Common carp | adult | W | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | Y | N | FW | in situ | N/I | N/I | N/I | 0.00037 | muscle | enzyme(s) | N/I | N/I | N/I | N/I | IP 1275 | females, EROD activity, 0.93-8.7 TEQ/L | Sakamoto et al. 2003. Cytochrome P450 induction and gonadal st.... Chemosphere 51:491-500. |
Cyprinus carpio | 15439 | F | Common carp | adult | W | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | Y | N | FW | in situ | N/I | N/I | N/I | 0.00037 | muscle | indice of condition | N/I | N/I | N/I | N/I | IP 221 | females, gonad somatic index, 0.93-8.7 TEQ/L | Sakamoto et al. 2003. Cytochrome P450 induction and gonadal st.... Chemosphere 51:491-500. |
Cyprinus carpio | 15440 | F | Common carp | adult | W | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | Y | N | FW | in situ | N/I | N/I | N/I | 0.00037 | muscle | physiological | N/I | N/I | N/I | N/I | IP 630 | females, CYP1A content, 0.93-8.7 TEQ/L | Sakamoto et al. 2003. Cytochrome P450 induction and gonadal st.... Chemosphere 51:491-500. |
Cyprinus carpio | 15441 | F | Common carp | adult | W | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | Y | N | FW | in situ | N/I | N/I | N/I | 0.00098 | muscle | physiological | N/I | N/I | N/I | N/I | ED 107 | males, CF, 0.93-8.7 TEQ/L | Sakamoto et al. 2003. Cytochrome P450 induction and gonadal st.... Chemosphere 51:491-500. |
Cyprinus carpio | 15442 | F | Common carp | adult | W | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | Y | N | FW | in situ | N/I | N/I | N/I | 0.00098 | muscle | physiological | N/I | N/I | N/I | N/I | NOEC | males, CSI, 0.93-8.7 TEQ/L | Sakamoto et al. 2003. Cytochrome P450 induction and gonadal st.... Chemosphere 51:491-500. |
Cyprinus carpio | 15443 | F | Common carp | adult | W | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | Y | N | FW | in situ | N/I | N/I | N/I | 0.00037 | muscle | physiological | N/I | N/I | N/I | N/I | ED 107 | females, CF, 0.93-8.7 TEQ/L | Sakamoto et al. 2003. Cytochrome P450 induction and gonadal st.... Chemosphere 51:491-500. |
Cyprinus carpio | 15444 | F | Common carp | adult | W | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | Y | N | FW | in situ | N/I | N/I | N/I | 0.00037 | muscle | physiological | N/I | N/I | N/I | N/I | ED 38 | females, serum estrogen, 0.93-8.7 TEQ/L | Sakamoto et al. 2003. Cytochrome P450 induction and gonadal st.... Chemosphere 51:491-500. |
Cyprinus carpio | 15445 | F | Common carp | adult | W | 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 1746-01-6 | Y | N | FW | in situ | N/I | N/I | N/I | 0.00098 | muscle | enzyme(s) | N/I | N/I | N/I | N/I | NOEC | males, EROD, 0.93-8.7 TEQ/L | Sakamoto et al. 2003. Cytochrome P450 induction and gonadal st.... Chemosphere 51:491-500. |
Carassius auratus | 2362 | L | goldfish | adult | N/I | 2,8-Dichlorodibenzo-p-dioxin | 38964-22-6 | Y | N/I | FW | aqueous | 9.2 µg/L | N/I | 4 | 1.5 | whole body | mortality | N/I | N/I | N/I | N/I | LOEC | Lethal body burden | Sijm and Opperhuizen. 1988. Biotransformation, bioaccumulation and l.... Chemosphere 17:83-99. |
Carassius auratus | 2363 | L | goldfish | adult | N/I | 2,8-Dichlorodibenzo-p-dioxin | 38964-22-6 | Y | N/I | FW | aqueous | 2.6 µg/L | N/I | 4 | 0.11 | whole body | mortality | NEF | N/I | N/I | N/I | NOEC | Concurrent exposure to pentachlorobenzene | Sijm and Opperhuizen. 1988. Biotransformation, bioaccumulation and l.... Chemosphere 17:83-99. |
Carassius auratus | 2364 | L | goldfish | adult | N/I | 2,8-Dichlorodibenzo-p-dioxin | 38964-22-6 | Y | N/I | FW | aqueous | 8.1 µg/L | N/I | 4 | 3 | whole body | behavior | DEC | N/I | Yes | N/I | LOEC | immobility but still ventilating | Sijm et al. 1993. The effect of the biotransformation inhi.... Aquat Toxicol 27:345-360. |
Carassius auratus | 2365 | L | goldfish | adult | N/I | 2,8-Dichlorodibenzo-p-dioxin | 38964-22-6 | Y | N/I | FW | aqueous | 8.1 µg/L | N/I | 4 | 6 | whole body | mortality | N/I | N/I | N/I | N/I | LOEC | Lethal body burden | Sijm et al. 1993. The effect of the biotransformation inhi.... Aquat Toxicol 27:345-360. |
Carassius auratus | 2366 | L | goldfish | adult | N/I | 2,8-Dichlorodibenzo-p-dioxin | 38964-22-6 | Y | N/I | FW | aqueous | 8.1 µg/L | N/I | 4 | 3 | whole body | mortality | N/I | N/I | N/I | N/I | NOEC | Residue in surviving fish | Sijm et al. 1993. The effect of the biotransformation inhi.... Aquat Toxicol 27:345-360. |